Summary: The highly lethal brain cancer glioblastoma (GBM) poses a daunting challenge because the blood-brain barrier renders potentially druggable amplified or mutated oncoproteins relatively inaccessible.Here, we identify sphingomyelin phosphodiesterase 1 (SMPD1), an enzyme that regulates the conversion of sphingomyelin to ceramide, as an actiona
Rapid evaluation model for EOR techniques applicability of gas flooding, foam flooding and surfactant flooding based on modified fractional flow theory
Abstract Before a wide range of enhanced oil recovery (EOR) techniques were implemented for an oilfield, the EOR potential and economic evaluation of the techniques should be evaluated in advance for each reservoir to determine which EOR technique was proper.In an oilfield developed with fluvial delta reservoirs, the complicated distribution of sca
Distributions, long term trends and emissions of four perfluorocarbons in remote parts of the atmosphere and firn air
We report the first data set of atmospheric abundances for the following four Fire Guard perfluoroalkanes: n-decafluorobutane (n-C<sub>4</sub>F<sub>10</sub>), n-dodecafluoropentane (n-C<sub>5</sub>F<sub>12</sub>), n-tetradecafluorohexane (n-C<sub>6</sub>F<sub>14</sub>) and n-he